Discovery of cyclic sulfonamide derivatives as potent inhibitors of SARS-CoV-2
Young Sup Shin, Jun Young Lee, Soojin Noh, Yoonna Kwak, Sangeun Jeon, Sunoh Kwon, Young-Hee Jin, Min Seong Jang, Seungtaek Kim, Jong Hwan Song, Hyoung Rae Kim, Chul Min Park
Topics & Concepts
SulfonamidehERGChemistryCytotoxicityMetabolic stabilitySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PharmacologyCoronavirus disease 2019 (COVID-19)In vitroStereochemistryBiochemistryMedicineInternal medicineDiseaseInfectious disease (medical specialty)Potassium channelComputational Drug Discovery MethodsEnzyme function and inhibitionElectrochemical sensors and biosensors