A Review of Catecholamine Associated Cardiomyopathies and Channelopathies
Pooja Sethi, Craig Davidson Peiris
Abstract
Conditions associated with states of catecholamine toxicity are pheochromocytoma, paraganglioma, Takotsubo's cardiomyopathy, and catecholaminergic polymorphic ventricular tachycardia. This article defines these conditions along with relevant diagnostic and prognostic factors. The role of catecholamines in these conditions are compared and contrasted. Emphasis is given to the role of endothelial dysfunction as a possible etiologic factor in cardiomyopathy associated with excess catecholamines.
Topics & Concepts
Catecholaminergic polymorphic ventricular tachycardiaMedicinePheochromocytomaCardiomyopathyCatecholamineCatecholaminergicParagangliomaInternal medicineCardiologyShort QT syndromeEpinephrineTachycardiaHeart failurePathologyLong QT syndromeRyanodine receptor 2QT intervalRyanodine receptorCalciumTakotsubo Cardiomyopathy and Associated PhenomenaAdrenal and Paraganglionic TumorsCardiac Imaging and Diagnostics