Downregulation of FOXO6 alleviates hypoxia-induced apoptosis and oxidative stress in cardiomyocytes by enhancing Nrf2 activation via upregulation of SIRT6
Aiping Jin, Qianrong Zhang, Shulin Li, Bing Li
Topics & Concepts
Gene knockdownDownregulation and upregulationCardioprotectionOxidative stressCell biologyChemistryApoptosisSignal transductionBiologyIschemiaBiochemistryMedicineInternal medicineGeneFOXO transcription factor regulationSirtuins and Resveratrol in MedicineCancer-related molecular mechanisms research