Outcome After Protontherapy for Progression or Recurrence of Surgically Treated Meningioma
Charles Champeaux, Joconde Weller
Abstract
BACKGROUND: To assess the outcome after meningioma surgery and protontherapy (PT). METHODS: We processed the French Système National des Données de Santé database to retrieve appropriate cases of meningiomas operated and irradiated between 2008 and 2017. Survival methods were implemented. RESULTS: =0.009) remained significantly associated to a reduced OS. CONCLUSION: Five-year PFS and OS after meningioma surgery and PT is favourable but impaired for older patients with high level of morbidities, tumour of the convexity, malignant histopathology and for those requiring CSF shunting. Further inclusion and prolonged follow-up is required to assess other predictors such as sex, tumour volume, or given dose.
Topics & Concepts
MedicineInterquartile rangeHazard ratioConfidence intervalMeningiomaSurgeryRadiosurgeryRadiation therapyInternal medicineMeningioma and schwannoma managementHead and Neck Surgical OncologyGlioma Diagnosis and Treatment