Targeting Nrf2 for ferroptosis-based therapy: Implications for overcoming ferroptosis evasion and therapy resistance in cancer

Jaewang Lee, Jong‐Lyel Roh

2023Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease67 citationsDOI

Topics & Concepts

GPX4Cancer cellLipid peroxidationCancerCancer researchKEAP1Programmed cell deathBiologyCell biologyOxidative stressApoptosisBiochemistryGeneTranscription factorSuperoxide dismutaseGeneticsGlutathione peroxidaseFerroptosis and cancer prognosisCancer, Lipids, and MetabolismCancer-related molecular mechanisms research