Targeting Aryl Hydrocarbon Receptor Signaling Enhances Type I Interferon-Independent Resistance to Herpes Simplex Virus
Jincheng Chen, Juan Liang, Hui Xu, Wenqi Liu, Shuyan Liu, Lian Duan, Fang Li, Zhaoqin Wang, Yingxia Liu, Brian P. McSharry, Carl G. Feng, Guoliang Zhang
Abstract
This study describes how a virus might utilize host aryl hydrocarbon receptor signaling to promote its replication, even in the presence of type I interferons.
Topics & Concepts
Aryl hydrocarbon receptorHerpes simplex virusViral replicationInterferonBiologyVirusReceptorVirologySignal transductionCell biologyTranscription factorGeneticsGeneImmune Response and InflammationImmune Cell Function and InteractionT-cell and B-cell Immunology