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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Lorenzo Sborgi, Sebastian Rühl, Estefania Mulvihill, Joka Pipercevic, Rosalie Heilig, Henning Stahlberg, Christopher J. Farady, Daniel J. Müller, Petr Brož, Sebastian Hiller

2016The EMBO Journal1,158 citationsDOIOpen Access PDF

Topics & Concepts

BiologyMechanism (biology)Cell biologyProgrammed cell deathBiophysicsCell membraneMembraneBiochemistryApoptosisEpistemologyPhilosophyInflammasome and immune disordersCell death mechanisms and regulationStreptococcal Infections and Treatments
GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death | Litcius