Prognostic Impact of Bronchoalveolar Lavage Fluid Galactomannan and Aspergillus Culture Results on Survival in COVID-19 Intensive Care Unit Patients: a <i>Post Hoc</i> Analysis from the European Confederation of Medical Mycology (ECMM) COVID-19-Associated Pulmonary Aspergillosis Study
Daniele Roberto Giacobbe, Juergen Prattes, Joost Wauters, Silvia Dettori, Alessio Signori, Jon Salmanton‐García, Johan Maertens, Marc Bourgeois, Marijke Reynders, Lynn Rutsaert, Niels Van Regenmortel, Piet Lormans, Simon Feys, Н Н Климко, О. В. Шадривова, Oliver A. Cornely, Riina Rautemaa‐Richardson, Philipp Koehler, Katrien Lagrou, Matteo Bassetti, Martin Hoenigl
Abstract
= 0.008). The other independent predictors of 90-day mortality were increasing age and active malignant disease. In conclusion, the combination of positive BALF GM and positive BALF Aspergillus culture was associated with increased 90-day mortality in critically ill patients with COVID-19. Additional study is needed to explore the possible prognostic value of other BALF markers.
Topics & Concepts
MedicineBronchoalveolar lavageInternal medicineIntensive care unitHazard ratioPost-hoc analysisGalactomannanAspergillosisPneumoniaConfidence intervalImmunologyGastroenterologyLungAntifungal resistance and susceptibilityInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisNosocomial Infections in ICU