Artemether relieves liver fibrosis by triggering ferroptosis in hepatic stellate cells via DHHC12-mediated S-palmitoylation of the BECN1 protein
Mengran Li, Yuqi Sun, Yuyao Wei, Yujia Li, Jiangjuan Shao, Mei Guo, Shizhong Zheng, Zili Zhang
Topics & Concepts
Hepatic stellate cellPalmitoylationChemistryHepatic fibrosisBECN1Cell biologyCancer researchFibrosisAutophagyMedicineBiologyInternal medicineBiochemistryApoptosisEnzymeCysteineFerroptosis and cancer prognosisLiver physiology and pathologyCholangiocarcinoma and Gallbladder Cancer Studies