A Single-Molecule Surface-Based Platform to Detect the Assembly and Function of the Human RNA Polymerase II Transcription Machinery
Sang Ryul Park, J. Hauver, Yunxiang Zhang, Andrey Revyakin, Robert A. Coleman, Robert Tjian, Steven Chu, Alexandros Pertsinidis
Topics & Concepts
BiomoleculePolymeraseBiophysicsBiocompatibilityMacromoleculeTranscription (linguistics)PEG ratioRNAPolyethylene glycolChemistryNanotechnologyMoleculeRNA polymerase IIRNA polymeraseDNACell biologyBiochemistryMaterials scienceBiologyPromoterGeneGene expressionEconomicsLinguisticsFinanceOrganic chemistryPhilosophyAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryMolecular Junctions and Nanostructures