Negative regulation of IL-8 in human astrocytes depends on β-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction
KaReisha F. Robinson, Srinivas D. Narasipura, Jennillee Wallace, Ethan Ritz, Lena Al‐Harthi
Topics & Concepts
TCF4Chromatin immunoprecipitationTranscription factorActivating transcription factor 2Cell biologyTranscription (linguistics)BiologyPromoterTranscriptional regulationMolecular biologyChemistryEnhancerGene expressionGeneGeneticsLinguisticsPhilosophyNeuroinflammation and Neurodegeneration Mechanismsinterferon and immune responsesCytokine Signaling Pathways and Interactions