Dexmedetomidine enhances Mitophagy via PINK1 to alleviate hippocampal neuronal Pyroptosis and improve postoperative cognitive dysfunction in elderly rat
Yayu Chen, Gen Wei, Xiaojin Feng, Enjun Lei, Lieliang Zhang
Topics & Concepts
PyroptosisAutophagyHippocampal formationMitophagyPINK1Postoperative cognitive dysfunctionDownregulation and upregulationPharmacologyMitochondrial fissionNeuroscienceHippocampusMedicineMitochondrionChemistryCell biologyBiologyProgrammed cell deathApoptosisCognitionBiochemistryGeneIntensive Care Unit Cognitive DisordersAnesthesia and Neurotoxicity Research