The diagnostic and prognostic role of neutrophil-to-lymphocyte ratio in COVID-19: a systematic review and meta-analysis
Ahmed Abdelaal Ahmed Mahmoud, Mohamed Gomaa Kamel, M Hamza, Ehab Farag, Hany Mahmoud Yassin, Mohamed Elayashy, Amr Ahmed Naguib, Mohamed Wagih, Fatma Abd‐Elshahed Abd‐Elhay, Haytham Zien Algameel, Mohammed Yousef, Andrew Purcell, Mohamed Helmy
Abstract
We found significantly higher levels of NLR in advanced stages compared to earlier stages of COVID-19 with good accuracy to diagnose and predict the disease outcome, especially mortality prediction. A close evaluation of critical SARS-CoV-2 patients and efficient early management are essential measures to decrease mortality. NLR could help in assessing the resource allocation in severe COVID-19 patients even in restricted settings.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)MedicineNeutrophil to lymphocyte ratioBiomarkerMeta-analysisSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Lymphocyte2019-20 coronavirus outbreakImmunologyDiagnostic biomarkerInternal medicinePathologyDiagnostic accuracyDiseaseBiologyInfectious disease (medical specialty)OutbreakBiochemistryCOVID-19 Clinical Research StudiesCOVID-19 Impact on ReproductionLong-Term Effects of COVID-19