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Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H+] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes

Yuxin Zhang, Xiurui Liang, Jing Guan, Jiaqi Jin, Yi Zhang, Fan Xu, Jihua Fu

2022Toxicology and Applied Pharmacology10 citationsDOI

Topics & Concepts

Mitochondrial respiratory chainMitochondrionCell biologyMitochondrial fissionMitochondrial permeability transition poreMitochondrial ROSReactive oxygen speciesDownregulation and upregulationApoptosisChemistryBiologyMolecular biologyProgrammed cell deathBiochemistryGeneDrug-Induced Hepatotoxicity and ProtectionMetabolism and Genetic DisordersMitochondrial Function and Pathology
Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H+] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes | Litcius