Impact of corticosteroids on efficacy of BCMA targeted CAR-T therapy in multiple myeloma
Eva Duvalyan, Nina Shah, Mimi Lo, Thomas G. Martin, Jeffrey L. Wolf, Alfred Chung, Shagun Arora, Chiung‐Yu Huang, Sandy W. Wong
Abstract
B-cell maturation antigen (BCMA) directed chimeric antigen receptor T-cell therapy (CAR-T) has shown unprecedented efficacy in multiple myeloma (MM). CAR-T toxicities in the acute period, cytokine ...
Topics & Concepts
BiologyManagementLibrary scienceComputer scienceEconomicsCAR-T cell therapy researchMultiple Myeloma Research and TreatmentsProtein Degradation and Inhibitors