Ultrasonic De-cross-linking of the pH- and Magneto-Responsive PHEMA/PMMA Microgel to Janus Nanoparticles: A New Synthesis Based on “Grafting from”/“Grafting to” Polymerization
Rahim Ghanbarinia Firozjah, Amirhossein Sadeghi, Sepideh Khoee
Abstract
-PHEMA nanoparticle. Transmission electron microscopy (TEM) was used to confirm the precise deposition of polymers and the Janus structure. The MTX release of US-synthesized Janus NPs was studied in PBS at pH values of 7.4 and 5.8. The release data were analyzed using the Excel add-in DDSolver program to evaluate the kinetics of the drug release process from the nanocarrier under different pH values.
Topics & Concepts
Surface modificationMethacrylateMaterials scienceAtom-transfer radical-polymerizationPolymerizationNanoparticlePolymer chemistryPolymerChemical engineeringReversible addition−fragmentation chain-transfer polymerizationRadical polymerizationNanotechnologyComposite materialEngineeringPickering emulsions and particle stabilizationElectrohydrodynamics and Fluid DynamicsNanoparticle-Based Drug Delivery