Ameliorative effects of mangiferin derivative TPX on insulin resistance via PI3K/AKT and AMPK signaling pathways in human HepG2 and HL-7702 hepatocytes
Xiangcheng Fan, Guangyang Jiao, Tao Pang, Tao Wen, Zhiqing He, Jun Han, Feng Zhang, Wansheng Chen
Topics & Concepts
GLUT4Insulin resistanceAMPKGlucose uptakeProtein kinase BGlucose transporterGlycogen synthaseInsulin receptorInsulinInternal medicineEndocrinologyAMP-activated protein kinasePI3K/AKT/mTOR pathwayChemistryGlycogenProtein kinase ABiochemistrySignal transductionBiologyPhosphorylationMedicineMangiferin and Mango ExtractsMetabolism, Diabetes, and CancerGinger and Zingiberaceae research