Litcius/Paper detail

High potency EDC-crosslinked bovine serum albumin nanoencapsulation of berberine enhances <i>in vitro</i> anticancer efficacy against glioblastoma by inducing ROS mediated cell apoptosis

Sayantan Ghosh, Puja Das, Bismita Nayak

2022New Journal of Chemistry14 citationsDOI

Abstract

EDC-crosslinked BER–BSA NPs effectively inhibit migration and induce apoptosis associated with ROS generation and mitochondrial membrane potential disruption in glioblastoma.

Topics & Concepts

ChemistryBovine serum albuminApoptosisBerberineIn vitroReactive oxygen speciesPotencyGlioblastomaViability assayPharmacologyCancer researchBiochemistryBiologyMedicineBerberine and alkaloids researchCannabis and Cannabinoid ResearchAlkaloids: synthesis and pharmacology