Establishment of animal models and behavioral studies for autism spectrum disorders
Daiyan Jiao, Yingkai Xu, Fei Tian, Yaqing Zhou, Dong Chen, Yujue Wang
Abstract
In recent years, the incidence of autism spectrum disorder (ASD) has increased, but the etiology and pathogenesis remain unclear. In this narrative review, we review and systematically summarize the methods used to construct animal models to study ASD and the related behavioral studies based on recent literature. Utilization of various ASD animal models can complement research on the etiology, pathogenesis, and core behaviors of ASD, providing information and a foundation for further basic research and clinical treatment of ASD.
Topics & Concepts
EtiologyAutismMedicineAutism spectrum disorderConstruct (python library)Narrative reviewAnimal modelComplement (music)Clinical psychologyPsychiatryIntensive care medicineChemistryEndocrinologyPhenotypeBiochemistryComputer scienceComplementationGeneProgramming languageAutism Spectrum Disorder ResearchGenetics and Neurodevelopmental DisordersNerve injury and regeneration