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Rapid and efficient degradation of endogenous proteins in vivo identifies stage-specific roles of RNA Pol II pausing in mammalian development

Abderhman Abuhashem, Andrew S. Lee, Alexandra L. Joyner, Anna‐Katerina Hadjantonakis

2022Developmental Cell53 citationsDOIOpen Access PDF

Topics & Concepts

DegronBiologyIn vivoCell biologyFunction (biology)Protein degradationComputational biologyUbiquitinBiochemistryGeneticsGeneUbiquitin ligaseRNA Research and SplicingProtein Degradation and InhibitorsCRISPR and Genetic Engineering
Rapid and efficient degradation of endogenous proteins in vivo identifies stage-specific roles of RNA Pol II pausing in mammalian development | Litcius