A chlorogenic acid functional strategy of anti-inflammation, anti-coagulation and promoted endothelial proliferation for bioprosthetic artificial heart valves
Xiaotong Chen, Tao Yu, Qunshou Kong, Hong Xu, Zhiyu Zhao, Gaocan Li, Haojun Fan, Yunbing Wang
Abstract
experimental results show that the functional BHV material OX-CA-PP exhibits superior anti-inflammation, improved anti-coagulation, minimal calcification and promoted proliferation of endothelial cells, showing that this non-glutaraldehyde functional strategy has great potential for the application of BHVs and providing a promising reference for other implanted biomaterials.
Topics & Concepts
Chlorogenic acidCoagulationInflammationArtificial heartCardiologyMaterials scienceMedicineInternal medicineChemistryFood scienceCardiac Valve Diseases and TreatmentsCardiac and Coronary Surgery TechniquesCardiac Ischemia and Reperfusion