Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors
Amr El‐Demerdash, Ahmed A. Al‐Karmalawy, Tarek Mohamed Abd El‐Aziz, Sameh S. Elhady, Khaled M. Darwish, Ahmed H.E. Hassan
Abstract
studies regarding the examined marine products either alone or in combination paving the way for promising lead molecules.
Topics & Concepts
ProteaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakVirologyBiologyMicrobiologyEnzymeBiochemistryMedicineInfectious disease (medical specialty)DiseaseOutbreakPathologyComputational Drug Discovery MethodsMicrobial Natural Products and BiosynthesisMarine Sponges and Natural Products