Impact of anticoagulation prior to COVID-19 infection: a propensity score–matched cohort study
Douglas Tremblay, Maaike van Gerwen, Mathilda Alsen, Santiago Thibaud, Alaina J. Kessler, Sangeetha Venugopal, Iman Makki, Qian Qin, Sirish Dharmapuri, Tomi Jun, Sheena Bhalla, Shana Berwick, Jonathan Feld, John Mascarenhas, Kevin Troy, Caroline Cromwell, Andrew Dunn, William Oh, Leonard Naymagon
Abstract
Tremblay and colleagues asked whether patients receiving either routine anticoagulation or antiplatelet therapy for existing conditions prior to becoming ill with COVID-19 have different outcomes from patients receiving neither therapy. After matching for existing comorbidities, this retrospective observational study finds no evidence for an effect of prediagnosis anticoagulation on mortality.
Topics & Concepts
Propensity score matchingMedicineObservational studyRetrospective cohort studyCoronavirus disease 2019 (COVID-19)ComorbidityCohort studyInternal medicineIntensive care medicineMEDLINECohortDiseaseLawPolitical scienceInfectious disease (medical specialty)COVID-19 Clinical Research StudiesLong-Term Effects of COVID-19COVID-19 and healthcare impacts