Facile one pot synthesis of 2-substituted benzimidazole derivatives under mild conditions by using engineered MgO@DFNS as heterogeneous catalyst
Suman Kusuma, Dipak B. Bawiskar, Chob Singh, Pratheep Panneerselvam, Pradipta Sinha, Akshaya K. Samal, Arvind H. Jadhav
Abstract
-phenylenediamine, and various aromatic and aliphatic aldehydes under ambient temperature. The catalyst produced a clean reaction profile with excellent yields in a shorter time under the umbrella of green chemistry. The effect of reaction parameters such as the effect of time, catalyst dosage, loading of MgO, effect of solvents and effect of different homo and heterogeneous catalyst were also tested. Furthermore, to understand the scope of the catalyst different substituted diamines and substituted aldehydes were reacted and obtained desired products in good to efficient yield. In addition, a recyclability study was also conducted and it was observed that the catalyst could be recycled for up to six cycles without noticeable changes in the morphology and activity. We believe that the present methodology gave several advantages such as an eco-friendly method, easy work-up, good selectivity, high yields and quick recovery of catalyst. MgO@DFNS is highly stable for several cycles without significant loss of its activity, which possibly demonstrates its applicability at the industrial scale.