Probing the serum albumin binding site of fenamates and photochemical protein labeling with a fluorescent dye
Tao Deng, Jing Zhao, Danfeng Peng, Xinqian He, Xinan Huang, Chaozhan Lin, Chenchen Zhu, Lei Wang, Fang Liu
Abstract
at 303 K). More interestingly, TTPy enables fluorescent labeling of HSA upon visible light irradiation. This study provides promising ways for HSA drug binding site identification and photochemical protein labeling.
Topics & Concepts
FluorescenceChemistryPhotochemistryBinding siteBiophysicsAlbuminSerum albuminFluorescent proteinFluoresceinGreen fluorescent proteinBiochemistryBiologyPhysicsGeneQuantum mechanicsProtein Interaction Studies and Fluorescence AnalysisDrug Transport and Resistance MechanismsMonoclonal and Polyclonal Antibodies Research