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Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription

Yanfen Zhu, Amit D. Gujar, Chee‐Hong Wong, Harianto Tjong, Chew Yee Ngan, Liang Gong, Yi‐An Chen, Hoon Kim, Jihe Liu, Meihong Li, Adam Mil-Homens, Rahul Maurya, Chris Kuhlberg, Fanyue Sun, Eunhee Yi, Ana C. deCarvalho, Yijun Ruan, Roel G.W. Verhaak, Chia‐Lin Wei

2021Cancer Cell289 citationsDOIOpen Access PDF

Topics & Concepts

EnhancerBiologyChromatinExtrachromosomal DNAGeneticsGenomeGeneTranscription factorCancer Genomics and DiagnosticsGenomics and Chromatin DynamicsEpigenetics and DNA Methylation
Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription | Litcius