Litcius/Paper detail

DNA templated Click Chemistry via 5-vinyl-2′-deoxyuridine and an acridine-tetrazine conjugate induces DNA damage and apoptosis in cancer cells

Yizhu Li, Yurong Ling, Morten O. Loehr, Sabrina Chaabane, Oh Wan Cheng, Kaifeng Zhao, Chao Wu, Moritz Büscher, Jana M. Weber, Daria Stomakhine, Marina Munker, Ronja Pientka, Sarah B Christ, Matthias Dobbelstein, Nathan W. Luedtke

2023Life Sciences10 citationsDOIOpen Access PDF

Topics & Concepts

Comet assayApoptosisDNA damageCytotoxicityDeoxyuridineChemistryViability assayMolecular biologyCancer cellDNACell cycleFlow cytometryBiologyBiochemistryCancerIn vitroGeneticsClick Chemistry and ApplicationsDNA and Nucleic Acid ChemistryMetal complexes synthesis and properties