A single von Willebrand factor C-domain protein acts as an extracellular pattern-recognition receptor in the river prawn Macrobrachium nipponense
Nan Qin, Hehe Sun, Meike Lu, Jianhui Wang, Ting Tang, Fengsong Liu
Abstract
that mediates cellular immune responses by recognizing PAMPs, agglutinating invasive microbes, and promoting phagocytosis in hemocytes.
Topics & Concepts
BiologyPattern recognition receptorMicrobiologyPichia pastorisLipoteichoic acidPeptidoglycanInnate immune systemBacteriaRecombinant DNAReceptorBiochemistryStaphylococcus aureusGeneGeneticsInvertebrate Immune Response MechanismsAntimicrobial Peptides and ActivitiesAquaculture disease management and microbiota