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Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers

Xinying Yuan, Chun-Hong Song, Xiujuan Liu, Xiao Wang, Mei-Qi Jia, Wang Wang, Wen‐Bo Liu, Xiang-Jing Fu, Cheng‐Yun Jin, Jian Song, Sai‐Yang Zhang, Sai‐Yang Zhang

2023European Journal of Medicinal Chemistry24 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryTubulinApoptosisCancer cellIC50Cell cycleIn vivoBiochemistryPharmacologyCancerMicrotubuleStereochemistryIn vitroCell biologyBiologyGeneticsBiotechnologySynthesis and biological activityFerrocene Chemistry and ApplicationsSynthesis and Biological Evaluation
Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers | Litcius