Metformin ameliorates the NLPP3 inflammasome mediated pyroptosis by inhibiting the expression of NEK7 in diabetic periodontitis
Xinyi Zhou, Qian Wang, Lulingxiao Nie, Peng Zhang, Pengfei Zhao, Quan Yuan, Ning Ji, Yi Ding, Qi Wang
Topics & Concepts
PyroptosisInflammasomePeriodontitisPyrin domainMetforminInflammationProgrammed cell deathMedicineDiabetes mellitusProinflammatory cytokineCancer researchIn vivoCell biologyApoptosisImmunologyChemistryBiologyInternal medicineEndocrinologyBiochemistryBiotechnologyInflammasome and immune disordersOral microbiology and periodontitis researchAutophagy in Disease and Therapy