Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics
Yakir Reshef, Laurie Rumker, Joyce B. Kang, Aparna Nathan, Ilya Korsunsky, Samira Asgari, Megan Murray, D. Branch Moody, Soumya Raychaudhuri
Topics & Concepts
Computational biologyBiologySample size determinationPopulationIdentification (biology)Cluster (spacecraft)PhenotypeTranscriptomeAbundance (ecology)Evolutionary biologyGeneticsComputer scienceStatisticsGeneMedicineGene expressionMathematicsEnvironmental healthProgramming languageFisheryBotanySingle-cell and spatial transcriptomicsImmune cells in cancerinterferon and immune responses