Intestinal microbiota, intestinal permeability and the urogenital tract: is there a pathophysiological link?
Kateryna Priadko, Lucio Romano, Simone Olivieri, Maria Luisa Romeo, Biagio Barone, Carmine Sciorio, Lorenzo Spirito, Michele Morelli, Felice Crocetto, Davide Arcaniolo, Vincenzo Mirone, Marco Romano, Laura A. Napolitano
Abstract
Human gut microbiome is related to different clinical conditions and diseases. Recently several hypotheses have been theorized about a link between gut microbiota and genitourinary disease including urinary tract infections, and benign prostatic hyperplasia. Despite several data, underlying mechanisms still remain unclear. The aim of this review is to report the current state of knowledge in relation to urinary tract infections, benign prostatic hyperplasia and intestinal microbiota with a focus on its role in the development of disease and the underlying pathophysiologic mechanisms.