A commentary on the Spanish hypertension studies MAPEC and HYGIA
Björn Lemmer, Martin Middeke
Abstract
The recently published chronotherapeutic Spanish papers MAPEC and HYGIA proposing that antihypertensive drug treatment should be given at bedtime suffers from obvious deficiencies in study design and are not a valid basis for drug treatment of hypertension.
Topics & Concepts
BedtimeHypertension treatmentAntihypertensive drugDrugDrug treatmentMedicineInternal medicineBlood pressurePharmacologyBlood Pressure and Hypertension StudiesCardiovascular Syncope and Autonomic DisordersHeart Rate Variability and Autonomic Control