The extract of Polygala fallax Hemsl. slows the progression of diabetic nephropathy by targeting TLR4 anti-inflammation and MMP-2/9-mediated anti-fibrosis in vitro
Min Hui Wang, Xinyan Liu, Zelong Wang, Qin Xu
Topics & Concepts
TLR4ApoptosisDiabetic nephropathyInflammationWestern blotFibrosisDownregulation and upregulationProinflammatory cytokinePharmacologyCancer researchBiologyChemistryImmunologyMedicineEndocrinologyKidneyInternal medicineBiochemistryGeneChronic Kidney Disease and DiabetesNatural Antidiabetic Agents StudiesNatural Compound Pharmacology Studies