Antiproliferative activity of new pentacyclic triterpene and a saponin from <i>Gladiolus segetum</i> Ker-Gawl corms supported by molecular docking study
Adel M. Abd El-kader, Basma Khalaf Mahmoud, Dina Hajjar, Mamdouh F. A. Mohamed, Alaa M. Hayallah, Usama Ramadan Abdelmohsen
Abstract
. These biological results were in harmony with that of the molecular modeling study, which showed that the cytotoxic activity of compound 2 might occur through the inhibition of the HER-2 enzyme.
Topics & Concepts
TriterpeneCormSaponinChemistryOleananeStereochemistryGladiolusBotanyBiologyMedicineAlternative medicinePathologyPhytochemicals and Antioxidant ActivitiesNatural product bioactivities and synthesisPhytochemistry and Biological Activities