Expressing IL-15/IL-18 and CXCR2 improve infiltration and survival of EGFRvIII-targeting CAR-T cells in breast cancer
Sun Ruixin, Liu Yifan, Wu Chuanlong, Zhou Min, Luo Hong, Guoxiu Du, Liu Zhengyang, Sun Yansha, Dong Yiwei, Su Jingwen, Mingliang Fan, Shi Bizhi, Jiang Hua, Zonghai Li
Topics & Concepts
CXC chemokine receptorsCancer researchChimeric antigen receptorBreast cancerImmunologyBiologyCancerMedicineImmunotherapyInternal medicineImmune systemChemokineChemokine receptorCAR-T cell therapy researchImmune Cell Function and InteractionImmunotherapy and Immune Responses