Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma
Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph J.�Y. Sung, Leaf Huang, Rihe Liu, Alfred S.L. Cheng
Topics & Concepts
Tumor microenvironmentImmunotherapyCancer researchImmune systemCytotoxic T cellImmune checkpointCD8FibrosisHepatocellular carcinomaTumor progressionT cellCancer immunotherapyPD-L1MedicineImmunologyCancerBiologyPathologyInternal medicineIn vitroBiochemistryImmune cells in cancerCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction