Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers
Josephine R. Giles, Sasikanth Manne, Elizabeth Freilich, Derek A. Oldridge, Amy E. Baxter, Sangeeth M. George, Zeyu Chen, Hua Huang, Lakshmi Chilukuri, Mary Carberry, Lydia Giles, Nan‐ping Weng, Regina M. Young, Carl H. June, Lynn M. Schuchter, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Alexander C. Huang, Junwei Shi, E. John Wherry
Topics & Concepts
BiologyEpigeneticsChromatinCellular differentiationComputational biologyEffectorEnhancerT cellRegulation of gene expressionGeneticsGeneGene expressionCell biologyImmune systemCAR-T cell therapy researchSingle-cell and spatial transcriptomicsvaccines and immunoinformatics approaches