Litcius/Paper detail

Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers

Josephine R. Giles, Sasikanth Manne, Elizabeth Freilich, Derek A. Oldridge, Amy E. Baxter, Sangeeth M. George, Zeyu Chen, Hua Huang, Lakshmi Chilukuri, Mary Carberry, Lydia Giles, Nan‐ping Weng, Regina M. Young, Carl H. June, Lynn M. Schuchter, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Alexander C. Huang, Junwei Shi, E. John Wherry

2022Immunity122 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEpigeneticsChromatinCellular differentiationComputational biologyEffectorEnhancerT cellRegulation of gene expressionGeneticsGeneGene expressionCell biologyImmune systemCAR-T cell therapy researchSingle-cell and spatial transcriptomicsvaccines and immunoinformatics approaches