Metformin alleviates the depression-like behaviors of elderly apoE4 mice via improving glucose metabolism and mitochondrial biogenesis
Yingbin Lin, Xiaoman Dai, Jing Zhang, Xiaochun Chen
Topics & Concepts
MetforminTFAMEndocrinologyInternal medicineMitochondrial biogenesisApolipoprotein EPDK4MedicineHippocampusPyruvate dehydrogenase complexMitochondrionBiologyDiabetes mellitusBiochemistryEnzymeDiseaseDiet and metabolism studiesBipolar Disorder and TreatmentTryptophan and brain disorders