Dietary milk fat globule membrane supplementation during late gestation increased the growth of neonatal piglets by improving their plasma parameters, intestinal barriers, and fecal microbiota
Xiangyu Zhang, Yujun Wu, Hao Ye, Cuiping Feng, Dandan Han, Shiyu Tao, Yu Pi, Junying Zhao, Lijun Chen, Junjun Wang
Abstract
was positively correlated with the relative mRNA expressions of Occludin, Claudin-1, Claudin-2, Claudin-4, Mucin 13, TLR2, and TLR4. In conclusion, MFGM supplementation during late gestation improved the physiological status of sows by improving their plasma parameters and intestinal microecology. The improved provision of nutrients through the umbilical cord blood and optimized microbiota colonization in neonatal piglets were beneficial to the intestinal morphological structure and barrier functions, consequently improving the growth performance of neonates during lactation. These findings provide insights into the future applications of MFGM with regard to maternal-fetal nutrition and a new option for nutritional intervention of neonates through maternal dietary manipulation.