Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections
Daniele Mercatelli, Elisabetta Pedace, Pierangelo Veltri, Federico M. Giorgi, Pietro Hiram Guzzi
Abstract
Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It has been observed that lethality seems to be related to the age of patients. While ageing has been extensively demonstrated to be accompanied by some modifications at the gene expression level, a possible link with COVID-19 manifestation still need to be investigated at the molecular level.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakSars virusMedicineVirologyBiologyDemographyInternal medicineOutbreakDiseaseInfectious disease (medical specialty)SociologySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCOVID-19 and Mental Health