Litcius/Paper detail

Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer’s disease

Sai‐Sai Xie, Jing Liu, Chunli Tang, Chengyun Pang, Qing Li, Yuelian Qin, Xiaojie Nong, Zhipeng Zhang, Jie Guo, Maojun Cheng, Weizhong Tang, Ningsheng Liang, Neng Jiang

2020European Journal of Medicinal Chemistry27 citationsDOIOpen Access PDF

Topics & Concepts

RasagilineChemistryClorgylineMonoamine oxidase BMonoamine oxidaseIC50PharmacologyMonoamine neurotransmitterPharmacokineticsNeuroprotectionIn vitroBiochemistryEnzymeParkinson's diseaseReceptorDiseaseSerotoninMedicinePathologyAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesMedicinal Plants and Neuroprotection