The maternal-fetal transfer of passive immunity as a mechanism of transplacental nanoparticle drug delivery for prenatal therapies
Wai Hei Tse, Sean Higgins, Daywin Patel, Malcolm Xing, Adrian R. West, Hagar I. Labouta, Richard Keijzer
Abstract
) and immmunofluorescence of ZO-1 tight junction proteins. The results provide insight into the clinical applications of nanoparticles for prenatal therapies using the mechanism of the maternal-fetal transfer of passive immunity.
Topics & Concepts
TransplacentalFetusDrug deliveryNanoparticlePassive immunityNeonatal Fc receptorChemistryPlacentaFetal circulationBiophysicsChitosanAntibodyImmunityImmunologyMedicineNanotechnologyImmunoglobulin GPregnancyImmune systemMaterials scienceBiologyBiochemistryOrganic chemistryGeneticsReproductive System and PregnancyPregnancy and Medication ImpactCOVID-19 Impact on Reproduction