Chronic exposure to parabens promotes non-alcoholic fatty liver disease in association with the changes of the gut microbiota and lipid metabolism
Yilin Ren, Xinyi Shi, Jing Mu, Shenyin Liu, Xin Qian, Wenlong Pei, Shanhong Ni, Zhengduo Zhang, Zhengduo Zhang, Lei Li, Zhan Zhang, Zhan Zhang
Abstract
gut microbiota-dependent AA metabolism. These results highlight the need for reducing oral exposure to synthetic preservatives to improve metabolic disturbance under HFD conditions.
Topics & Concepts
Lipid metabolismFatty liverGut floraMetabolismMethylparabenBiologyBiochemistryOleic acidArachidonic acidMetaboliteChemistryEndocrinologyInternal medicineFood sciencePreservativeDiseaseMedicineEnzymeMetabolomics and Mass Spectrometry StudiesLiver Disease Diagnosis and TreatmentDiet and metabolism studies