Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery
Mingtan Tang, Lina Lozano Hernandez, Joy N. Reginald-Opara, Darren Svirskis, Euphemia Leung, Hongbo Wang, Zimei Wu
Topics & Concepts
GemcitabineCytidine deaminaseDeoxycytidinePancreatic cancerPharmacologyChemistryCancer researchChemotherapyMedicineInternal medicineCancerBiochemistryEnzymePancreatic and Hepatic Oncology ResearchEpigenetics and DNA MethylationCancer Genomics and Diagnostics