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A comprehensive review of recent advances in the biological activities of quinazolines

Hesham A. M. Gomaa

2022Chemical Biology & Drug Design39 citationsDOI

Abstract

Quinazoline heterocycles are critical in the development of medications. Quinazoline derivatives have been intensively researched, providing a wide range of compounds with diverse biological roles. The quinazoline nucleus has garnered a lot of attention in medical chemistry in recent years. It was assumed to be a pharmacophore component in the development of physiologically interesting drugs. This review is an attempt to increase the potential of quinazoline by highlighting a wide range of advancements demonstrated by numerous derivatives of the quinazoline moiety, as well as focusing on diverse pharmacological actions of the quinazoline moiety. This review compiles recent studies on the quinazoline moiety described in the literature by researchers.

Topics & Concepts

Computational biologyComputer scienceBiologyQuinazolinone synthesis and applicationsSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds
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