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Hematologic and biochemical reference intervals for 1‐month‐old specific‐pathogen‐free Landrace pigs

Changwen Li, Feng Wang, Rui Li, Muhammad Ishfaq, Hongyan Chen, Fangping Liu, Yun Liu

2021Veterinary Clinical Pathology21 citationsDOI

Abstract

BACKGROUND: Hematologic and biochemical reference intervals (RIs) provide valuable data for the nutritional status and clinical diagnosis of animals. However, the specific hematologic and biochemical RIs for specific-pathogen-free (SPF) Landrace pigs has not been determined. OBJECTIVE: The present study was designed to establish the hematologic and biochemical RIs for SPF 1-month-old Landrace pigs. METHODS: Blood samples were collected from the jugular vein of 105 SPF 1-month-old Landrace pigs (50 males and 55 females), and complete blood counts and biochemical examinations were performed. The mean, RI, and 90% confidence interval were calculated for each variable, and gender differences were analyzed. RESULTS: Reference intervals for SPF 1-month-old Landrace pigs were generated. The results revealed that there was generally no significant difference between male and female hematologic and serum biochemical variables (P > .05). However, a significant difference was noted in serum triglyceride concentrations between male and female pigs (P < .05). CONCLUSIONS: This study provides hematologic and biochemical RIs for SPF 1-month-old Landrace pigs and provides basic data for the research and application of SPF Landrace pigs as a laboratory animal.

Topics & Concepts

Specific-pathogen-freeHematologyBiologyConfidence intervalMedicinePhysiologyBlood countAnimal scienceTriglycerideAlanine aminotransferaseVeterinary medicineInternal medicineImmunologyCholesterolVirusClinical Laboratory Practices and Quality ControlAnimal health and immunologyReliability and Agreement in Measurement