Using a novel rapid alternating steering angles pulse sequence to evaluate the impact of theranostic ultrasound-mediated ultra-short pulse length on blood-brain barrier opening volume and closure, cavitation mapping, drug delivery feasibility, and safety
Alec J. Batts, Robin Ji, Rebecca L. Noel, Alina R. Kline-Schoder, Sua Bae, Nancy Kwon, Elisa E. Konofagou
Abstract
ThUS is a versatile single-array technique which exhibits the potential for investigating a variety of non-invasive therapeutic delivery applications in the brain.
Topics & Concepts
Biomedical engineeringMicrobubblesUltrasoundMagnetic resonance imagingFocused ultrasoundBlood–brain barrierTherapeutic ultrasoundDrug deliveryPhased arrayMaterials scienceMedicineComputer scienceRadiologyNanotechnologyCentral nervous systemTelecommunicationsEndocrinologyAntenna (radio)Ultrasound and Hyperthermia ApplicationsUltrasound Imaging and ElastographyPhotoacoustic and Ultrasonic Imaging