In Vitro Bacterial Adhesion and Biofilm Formation on Fully Absorbable Poly-4-hydroxybutyrate and Nonabsorbable Polypropylene Pelvic Floor Implants
Kim W. J. Verhorstert, Zeliha Güler, Leonie de Boer, Martijn Riool, Jan‐Paul W. R. Roovers, Sebastian A. J. Zaat
Abstract
incubation. These results show that in flat films, the polymer influences biofilm formation, demonstrated by a reduced biofilm formation on P4HB compared with PP flat films. In addition, the knitting design may affect bacterial adhesion. Despite certain design and material characteristics that give the knitted P4HB implants a higher surface area, this did not result in more bacterial adhesion and biofilm formation overall. Collectively, these results warrant further (pre)clinical investigations of P4HB pelvic floor implants.
Topics & Concepts
Materials scienceBiofilmAdhesionPolypropyleneIn vitroBiomedical engineeringComposite materialBacteriaMedicineBiologyBiochemistryGeneticsPelvic floor disorders treatmentsAnorectal Disease Treatments and OutcomesPelvic and Acetabular Injuries