Catalyst‐ and Additive‐Free Decarboxylative C‐4 Phosphorylation of Coumarin‐3‐Carboxylic Acids at Ambient Conditions
Goutam Brahmachari
Abstract
Abstract A catalyst‐ and additive‐free practical and green synthetic strategy for decarboxylative C‐4 phosphorylation of coumarin‐3‐carboxylic acids, for the first time, has been accomplished to access a series of substituted 4‐(diarylphosphoryl)chroman‐2‐ones at ambient conditions. The developed protocol is successfully applied to large‐scale synthesis. magnified image
Topics & Concepts
ChemistryCoumarinDecarboxylationCatalysisPhosphorylationCombinatorial chemistryOrganic chemistryCarboxylic acidBiochemistrySulfur-Based Synthesis TechniquesOrganophosphorus compounds synthesisChemical Synthesis and Reactions